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KMID : 0357919820160010013
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Korean Journal of Pathology
1982 Volume.16 No. 1 p.13 ~ p.18
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Effects of Storage on Immunoglobulin Concentration in Stored ACD Blood
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Abstract
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The present study was undertaken to assess the effects of storage on the stability of
plasma immunoglobulins (IgG, IgA, IgM and IgD) in ACD stored blood after periods of
storage up to 12 weeks at 4℃.
1) Blood was drawn from 5 healthy volunteer donors into acid-citrate-dextrose(ACD)
anticoagulant containers and placed in the blood bank refrigerator. Plasma
immunoglobulins were measured on all samples initially and every week up to 12 weeks
of storage at 4℃. Plasma immunoglobulins were measured by single radial
immunodiffusion method.
2) Results of analyses are presented and discussed. The coefficient of variation of test
samples is compared with that of standard quality control data (IgG: 8.8%, IgA: 7.9%,
IgM: 9.5% and IgD: 9.3%).
3) No significant differences were found in the concentrations of immunoglobulins
compared with the initial concentrations at the 3rd week(expiration date) and the 12th
week.
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